Sleep apnea
treatment options.
Different treatments support breathing in different ways. Your diagnosis, sleep study, health history, and preferences help determine the right plan.
Start with
the diagnosis.
Snoring and daytime tiredness can have several causes. A questionnaire cannot diagnose sleep apnea. A medical sleep evaluation helps distinguish obstructive sleep apnea from other sleep or breathing disorders before treatment is selected.
Need a diagnosis? We help coordinate sleep studies with local sleep specialists and telehealth providers. They can evaluate your symptoms, recommend appropriate testing, and review the results so you can make informed treatment decisions.
Already diagnosed? Bring your sleep study and tell us what you have tried. Do not stop prescribed treatment while exploring other options without guidance from your treating clinician.
Care provided
at RespAir Sleep.
Custom oral appliance therapy
A dentist-fitted appliance supports the lower jaw during sleep. Dr. DeSaix evaluates your teeth, bite, jaw health, and treatment needs, then works with you to select and adjust an appliance. Follow-up with your dentist and sleep clinician, including sleep testing, helps assess its effectiveness.
Explore oral appliance therapyHow oral appliances work · Appliance options
Combined therapy
For selected patients, an oral appliance can be used with PAP as part of a coordinated plan. It is not a reason to change pressure settings yourself.
Explore combined therapySnoring care
We evaluate treatment options for snoring after considering whether sleep apnea needs to be investigated.
Explore snoring treatmentOther established options.
A coordinated conversation.
RespAir works with your sleep physician and, when appropriate, refers you to providers who offer treatments beyond dental sleep medicine. Many patients use a combination of approaches, such as an oral appliance with PAP or weight management alongside nighttime treatment. We coordinate the dental part of your care while the appropriate provider manages each additional treatment.
Positive airway pressure: CPAP, APAP, and bilevel PAP
A PAP machine sends pressurized air through a tube to a mask over your nose, or your nose and mouth. The pressure helps hold the throat open during sleep so air can keep moving past tissues that would otherwise narrow or collapse. The main types differ in how they deliver that pressure:
- CPAP (continuous positive airway pressure) supplies one prescribed treatment pressure throughout the night to keep the airway open.
- APAP (auto-adjusting positive airway pressure) raises or lowers pressure within a prescribed range in response to changes in your breathing.
- Bilevel PAP (also called BPAP) provides a higher pressure when you breathe in and a lower pressure when you breathe out. It can meet particular pressure or breathing-support needs; it is not automatically a better choice for everyone.
Your sleep clinician selects the device and settings based on your diagnosis and treatment needs. CPAP and APAP are common choices for obstructive sleep apnea. Mask fit, comfort adjustments, and humidification can also make treatment easier to use consistently.
CPAP not working? Start hereWeight management and positional approaches
Weight management or changing sleep position may be part of a tailored plan. They do not automatically replace prescribed therapy.
Medication for a defined group of patients
Zepbound (tirzepatide) is FDA-approved for moderate-to-severe obstructive sleep apnea in adults with obesity, alongside a reduced-calorie diet and increased physical activity. That indication does not apply to every weight-loss drug or every person with sleep apnea. Discuss eligibility, risks, and monitoring with a prescribing clinician.
Myofunctional therapy
This guided program uses exercises for the tongue, mouth, and throat muscles. It may help selected patients as an addition to their treatment plan, but results and the strength of the evidence vary. A trained provider can assess whether it is appropriate, and your sleep clinician can determine how to check the response. RespAir does not provide myofunctional therapy directly.
Daytime tongue stimulation: eXciteOSA
eXciteOSA uses a removable mouthpiece to deliver electrical stimulation to the tongue muscles while you are awake. It is different from myofunctional exercises and from an oral appliance worn during sleep. The device is FDA-cleared for snoring and mild obstructive sleep apnea in adults age 18 and older; it is not a treatment for every level of sleep apnea. RespAir does not provide eXciteOSA directly. An appropriate treating provider can discuss eligibility and follow-up testing.
Surgery and implanted nerve stimulation
Procedures, including hypoglossal nerve stimulation such as Inspire, require specialist evaluation and specific eligibility assessment. Ask your sleep physician whether a referral makes sense.
New treatments
under investigation.
Researchers are exploring new ways to support breathing during sleep, including medicines that target airway muscles, breathing control, or obesity. Here are three approaches to watch. Their study results and availability are still evolving.
AD109: supporting airway muscle activity
This investigational combination of aroxybutynin and atomoxetine is designed to help maintain upper-airway muscle activity during sleep. Its application is under FDA review as of October 4, 2026. It has not yet been approved, so it is not currently an established treatment option.
Retatrutide: studying weight-related improvements
Retatrutide is an investigational medicine being studied for obesity and related conditions, including obstructive sleep apnea. Phase 3 results have been reported in people with obesity and sleep apnea. It remains investigational and is different from tirzepatide (Zepbound), which already has an FDA-approved indication for certain adults with sleep apnea.
Sulthiame: targeting breathing control
Also called sultiame, this medicine is being studied for its effects on breathing control during sleep. A phase 2 randomized trial reported improvements in sleep-apnea measures. Further research is needed to establish its role, longer-term safety, and which patients might benefit; it is not an approved treatment for obstructive sleep apnea.
These developments may broaden future choices. Your current plan should still be based on available treatments and follow-up with your care team; participating in research is a separate discussion with a study clinician.
Sources & further reading
Sources checked October 4, 2026. General education; individual care requires a clinical evaluation.
- NHLBI: Sleep apnea treatment
- AASM/AADSM: Oral appliance clinical guideline
- FDA: Zepbound approval for OSA
- Apnimed: AD109 application accepted for FDA review
- NHLBI: How CPAP works
- AASM: Positive airway pressure clinical guideline
- Randomized trial: Oropharyngeal exercises for OSA
- FDA: eXciteOSA clearance and indications
- Lilly: Retatrutide research and investigational status
- The Lancet: Phase 2 sulthiame trial
Find your
next step.
Bring your questions. We’ll help you plan a conversation with the right care team.